Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | HTRA2 | O43464 | 7/20 | 0.46 |
| ▸ | HTRA1 | Q92743 | 7/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403238 | 0.90 | ALB (0.58) | ALBESR1HTRA2HTRA1FOLH1 | |
| SCHEMBL23291875 | 0.86 | FOLH1 (0.54) | ALBESR1HTRA2HTRA1FOLH1 | |
| SCHEMBL14524697 | 0.85 | FOLH1 (0.59) | ALBESR1HTRA2HTRA1FOLH1 | |
| SCHEMBL4401348 | 0.85 | FOLH1 (0.59) | ALBESR1HTRA2HTRA1FOLH1 | |
| SCHEMBL4401282 | 0.81 | FOLH1 (0.60) | ALBESR1FOLH1CA12CA1 | |
| SCHEMBL15501046 | 0.80 | FOLH1 (0.59) | ALBESR1HTRA2HTRA1FOLH1 | |
| SCHEMBL9965269 | 0.77 | FOLH1 (0.52) | ALBESR1HTRA2HTRA1FOLH1 | |
| SCHEMBL8521611 | 0.75 | FOLH1 (0.49) | ALBESR1HTRA2HTRA1FOLH1 | |
| SCHEMBL18950709 | 0.75 | ESR1 (0.43) | ALBESR1HTRA2HTRA1FOLH1 | |
| SCHEMBL12262226 | 0.75 | ESR1 (0.53) | ALBESR1HTRA2HTRA1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2369006-B1 | Covalent tethering of functional groups to proteins | PROMEGA CORP (US) | 2014-03-12 | — | — | EP | disclosed |