Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 20/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2757820 | 0.88 | MIF (1.00) | MIFHDAC6 | |
| SCHEMBL15501132 | 0.87 | MIF (0.77) | MIFHDAC6 | |
| SCHEMBL667764 | 0.85 | MIF (1.00) | MIFHDAC6 | |
| SCHEMBL668287 | 0.85 | MIF (1.00) | MIFHDAC6 | |
| SCHEMBL455228 | 0.85 | MIF (1.00) | MIFHDAC6 | |
| SCHEMBL3225301 | 0.83 | MIF (0.70) | MIFHDAC6 | |
| SCHEMBL669136 | 0.81 | MIF (1.00) | MIFHDAC6 | |
| SCHEMBL15082890 | 0.81 | MIF (0.79) | MIFHDAC6 | |
| SCHEMBL14642447 | 0.81 | MIF (0.78) | MIFHDAC6 | |
| SCHEMBL12517503 | 0.79 | MIF (0.75) | MIFHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004192-B1 | MODIFIED MACROPHAGE MIGRATION INHIBITORY FACTOR INHIBITORS | THE FEINSTEIN INST MEDICAL RES (US) | 2014-03-12 | — | — | EP | disclosed |