Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15510154 | 0.89 | BACE1 (0.70) | BACE1CTSD | |
| SCHEMBL15509730 | 0.84 | BACE1 (0.77) | BACE1CTSD | |
| SCHEMBL15510362 | 0.83 | BACE1 (0.76) | BACE1CTSD | |
| SCHEMBL2013736 | 0.81 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL2009754 | 0.81 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL15510234 | 0.80 | BACE1 (0.70) | BACE1CTSD | |
| SCHEMBL2014001 | 0.80 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL2016459 | 0.80 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL2011233 | 0.79 | BACE1 (1.00) | BACE1CTSD | |
| SCHEMBL2015648 | 0.79 | BACE1 (1.00) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328903-B1 | SPIRO-TETRACYCLIC RING COMPOUNDS AS BETASECRETASE MODULATORS AND METHODS OF USE | AMGEN INC (US) | 2014-03-05 | — | — | EP | disclosed |