SCHEMBL15511154

SCHEMBL15511154

[c]1ccccc1-c1cncc(-c2cccnc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.50
ALDH1A1 P00352 3/20 0.50
CYP3A4 P08684 2/20 0.50
CYP1A2 P05177 1/20 0.50
MKNK1 Q9BUB5 2/20 0.45
MKNK2 Q9HBH9 2/20 0.45
CYP19A1 P11511 3/20 0.45
CYP11B1 P15538 3/20 0.45
CYP11B2 P19099 2/20 0.45
CYP17A1 P05093 1/20 0.45
CYP2C9 P11712 1/20 0.42
CYP2B6 P20813 1/20 0.42
CYP2C19 P33261 1/20 0.42
MEN1 O00255 1/20 0.42
PSIP1 O75475 1/20 0.42
AXL P30530 1/20 0.42
DYRK1A Q13627 1/20 0.41
DYRK1B Q9Y463 1/20 0.41
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9958003 0.90 CYP2A6 (0.50) CYP2A6ALDH1A1CYP3A4CYP1A2MKNK1
SCHEMBL28917460 0.88 MKNK1 (0.45) CYP2A6MKNK1MKNK2CYP19A1CYP11B1
SCHEMBL38500 0.88 CYP2A6 (0.54) CYP2A6ALDH1A1CYP3A4CYP1A2MKNK1
SCHEMBL9958537 0.86 CYP2A6 (0.54) CYP2A6ALDH1A1CYP3A4CYP1A2MKNK1
SCHEMBL30586094 0.80 CYP2A6 (0.79) CYP2A6ALDH1A1CYP3A4CYP1A2MKNK1
SCHEMBL30586096 0.80 CYP2A6 (0.79) CYP2A6ALDH1A1CYP3A4CYP1A2MKNK1
SCHEMBL21808801 0.80 CYP2A6 (0.79) CYP2A6ALDH1A1CYP3A4CYP1A2MKNK1
SCHEMBL9958153 0.78 CYP2A6 (0.47) CYP2A6ALDH1A1CYP3A4CYP1A2CYP11B1
SCHEMBL15496379 0.78 CYP2A6 (0.68) CYP2A6ALDH1A1CYP3A4CYP1A2MKNK1
SCHEMBL12068475 0.78 CYP2A6 (0.75) CYP2A6ALDH1A1CYP3A4CYP1A2MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9379336-B2 Compounds for use in light emitting devices NITTO DENKO CORPORATION (JP) 2016-06-28 US disclosed
US-20140061614-A1 COMPOUNDS FOR USE IN LIGHT EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2014-03-06 US disclosed