Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 19/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.49 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2070841 | 0.96 | HDAC1 (0.58) | HDAC1HDAC3HDAC2HDAC4HDAC6 | |
| SCHEMBL15514020 | 0.92 | HDAC1 (0.62) | HDAC1HDAC3HDAC2HDAC4HDAC6 | |
| SCHEMBL15513177 | 0.92 | HDAC1 (0.62) | HDAC1HDAC3HDAC2HDAC4HDAC6 | |
| SCHEMBL15513297 | 0.92 | HDAC1 (0.62) | HDAC1HDAC3HDAC2HDAC4HDAC6 | |
| SCHEMBL15513687 | 0.91 | HDAC1 (0.63) | HDAC1HDAC3HDAC2HDAC4HDAC6 | |
| SCHEMBL15512867 | 0.91 | HDAC1 (0.76) | HDAC1HDAC3HDAC2HDAC4HDAC6 | |
| SCHEMBL15514014 | 0.89 | HDAC1 (0.65) | HDAC1HDAC3HDAC2HDAC4HDAC6 | |
| Trifluoroacetic Acid SCHEMBL2070991 | 0.88 | HDAC1 (0.58) | HDAC1HDAC3HDAC2HDAC4HDAC6 | |
| Trifluoroacetic Acid SCHEMBL2071703 | 0.88 | HDAC1 (0.57) | HDAC1HDAC3HDAC2HDAC4HDAC6 | |
| Trifluoroacetic Acid SCHEMBL2073501 | 0.88 | HDAC1 (0.57) | HDAC1HDAC3HDAC2HDAC4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828171-B1 | HETEROCYCLE DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2014-03-12 | — | — | EP | claimed |