Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1534156 | 0.92 | TDP1 (0.44) | TDP1TP53OR51E2MAPK1MAPT | |
| Cadaverine Tartrate SCHEMBL536929 | 0.91 | TDP1 (0.43) | TDP1TP53OR51E2 | |
| Acetic Acid SCHEMBL10713831 | 0.90 | TDP1 (0.46) | TDP1OR51E2MAPK1MAPT | |
| Acetic Acid SCHEMBL20210837 | 0.90 | TDP1 (0.46) | TDP1OR51E2MAPK1MAPT | |
| SCHEMBL28596513 | 0.89 | OR51E2 (0.50) | TDP1TP53OR51E2 | |
| SCHEMBL9148281 | 0.89 | TDP1 (0.44) | TDP1MAPK1MAPT | |
| Acetone SCHEMBL29160638 | 0.88 | TDP1 (0.47) | TDP1MAPK1MAPT | |
| Bicarbonate SCHEMBL25422186 | 0.88 | TDP1 (0.45) | TDP1TP53OR51E2MAPK1MAPT | |
| SCHEMBL18322329 | 0.88 | TDP1 (0.54) | TDP1MAPK1 | |
| SCHEMBL7615057 | 0.88 | TDP1 (0.54) | TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2705879-A1 | COMBINATION OF OILS FOR ANTIPERSPIRANT COMPOSITIONS WITH IMPROVED WHITE MARK PROTECTION | Henkel AG&Co. KGAA (DE) | 2014-03-12 | — | — | EP | disclosed |