Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 3/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15196367 | 0.87 | GCK (0.42) | HTTFYNGCKCYP1A2CYP3A4 | |
| SCHEMBL2668582 | 0.87 | GCK (0.47) | L3MBTL1GCK | |
| SCHEMBL15514755 | 0.87 | MAP4K4 (0.38) | FEN1TNK2TRPA1ALOX5AP | |
| SCHEMBL15403264 | 0.81 | USP2 (0.48) | KMT2AKDM4ECA12CA1CA2 | |
| SCHEMBL15403575 | 0.79 | KDM4E (0.35) | MEN1KMT2AKDM4ECA12CA1 | |
| SCHEMBL2668523 | 0.76 | KDR (0.47) | SCN9A | |
| SCHEMBL1330058 | 0.76 | GCK (0.55) | L3MBTL1GCK | |
| SCHEMBL15404535 | 0.75 | GCK (0.43) | L3MBTL1GCK | |
| SCHEMBL15403747 | 0.74 | GCK (0.45) | RAB9AL3MBTL1GCKFEN1ALOX5AP | |
| SCHEMBL1331442 | 0.74 | GCK (0.55) | FYNGCKTNK2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140073658-A1 | Dipyridylamine Derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073658-A1 | Dipyridylamine Derivative | GCK, GCKR, GALK1 | MEN1 3108/4885KMT2A 2024/4885KDM4E 2457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.