Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.54 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31588148 | 1.00 | HTT (0.61) | HTTCYP11B1CYP11B2NCOA3CA1 | |
| Hydrochloric Acid SCHEMBL11816471 | 0.98 | HTT (0.59) | HTTCYP11B1CYP11B2NCOA3CA1 | |
| SCHEMBL27600515 | 0.98 | HTT (0.59) | HTTCYP11B1CYP11B2NCOA3CA1 | |
| SCHEMBL4062748 | 0.81 | HTT (0.44) | HTTCYP11B1CYP11B2PRKCZKDM4E | |
| SCHEMBL1447988 | 0.79 | HTT (0.43) | HTTCYP11B1CYP11B2PRKCZKDM4E | |
| SCHEMBL30183020 | 0.78 | HTT (0.59) | HTTCYP11B1CYP11B2NCOA3CDK5 | |
| SCHEMBL6876988 | 0.76 | HTT (0.41) | HTTCYP11B1CYP11B2PRKCZKDM4E | |
| SCHEMBL1202005 | 0.76 | HTT (1.00) | HTTCYP11B1CYP11B2NCOA3CA1 | |
| Hydrochloric Acid SCHEMBL31354899 | 0.76 | HTT (0.58) | HTTCYP11B1CYP11B2NCOA3CDK5 | |
| SCHEMBL15947624 | 0.75 | GRM5 (0.47) | HTTCYP11B1CYP11B2PRKCZKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120028308-A | Small molecule Raman probe, bar code probe, encoding method and application thereof | 北京大学 | 2025-05-23 | — | — | CN | claimed |
| CN-115605466-B | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-11-01 | — | — | CN | claimed |
| CN-116444750-A | Foaming polyurethane or polyurea water dispersion, preparation method and application | 万华化学集团股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-113620934-B | Alkylation method of nitrogen-containing heterocyclic compound in visible light-mediated micro-reaction device | 南京先进生物材料与过程装备研究院有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-115605466-A | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司（US） | 2023-01-13 | — | — | CN | claimed |
| CN-113620934-A | Alkylation method of nitrogen-containing heterocyclic compound in visible light-mediated micro-reaction device | 南京先进生物材料与过程装备研究院有限公司 | 2021-11-09 | — | — | CN | claimed |
| CN-110606716-A | Construction method of indoor partition wall | 广东优鼎装饰设计工程有限公司 | 2019-12-24 | — | — | CN | claimed |
| US-9469741-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2016-10-18 | — | — | US | claimed |
| EP-2203482-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORP (JP) | 2015-11-25 | — | — | EP | claimed |
| US-20150267031-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2015-09-24 | — | — | US | claimed |
| US-8314189-B2 | Polymers functionalized with heterocyclic nitrile compounds | BRIDGESTONE CORPORATION (JP) | 2012-11-20 | — | — | US | claimed |
| US-20100280217-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2010-11-04 | — | — | US | claimed |
| EP-2203438-A1 | CYANOISOQUINOLINE | H. Lundbeck A/S (DK) | 2010-07-07 | — | — | EP | claimed |
| EP-2203482-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | Bridgestone Corporation (JP) | 2010-07-07 | — | — | EP | claimed |
| EP-2069325-A2 | ISOQUINOLINE, QUINAZOLINE AND PHTHALAZINE DERIVATIVES | Serenex, Inc. (US) | 2009-06-17 | — | — | EP | claimed |
| WO-2009051702-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2009-04-23 | — | — | WO | claimed |
| WO-2009051700-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION (US) | 2009-04-23 | — | — | WO | claimed |
| US-20090099325-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC NITRILE COMPOUNDS | BRIDGESTONE CORPORATION | 2009-04-16 | — | — | US | claimed |
| WO-2009036766-A1 | CYANOISOQUINOLINE | H. LUNDBECK A/S (DK) | 2009-03-26 | — | — | WO | claimed |
| WO-2008024977-A2 | ISOQUINOLINE, QUINAZOLINE AND PHTHALAZINE DERIVATIVES | SERENEX, INC. (US) | 2008-02-28 | — | — | WO | claimed |