Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450308 | 0.82 | FFAR1 (0.68) | FFAR1HDAC4EPHX2ALDH1A1 | |
| SCHEMBL2239420 | 0.82 | FFAR1 (0.68) | FFAR1HDAC4EPHX2ALDH1A1 | |
| SCHEMBL21501053 | 0.82 | FFAR1 (0.68) | FFAR1HDAC4EPHX2ALDH1A1 | |
| SCHEMBL16804596 | 0.82 | FFAR1 (0.68) | FFAR1HDAC4EPHX2ALDH1A1 | |
| SCHEMBL440438 | 0.82 | FFAR1 (0.68) | FFAR1HDAC4EPHX2ALDH1A1 | |
| SCHEMBL1550764 | 0.81 | FFAR1 (1.00) | FFAR1HDAC4EPHX2ALDH1A1SLC9A1 | |
| SCHEMBL1550763 | 0.81 | FFAR1 (1.00) | FFAR1HDAC4EPHX2ALDH1A1SLC9A1 | |
| SCHEMBL6906683 | 0.80 | FFAR1 (0.56) | FFAR1HDAC4ALDH1A1SLC9A1 | |
| SCHEMBL1550250 | 0.80 | SLC6A2 (0.57) | FFAR1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL6906686 | 0.80 | FFAR1 (0.56) | FFAR1HDAC4ALDH1A1SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313360-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISEASES | Syddansk Universitet (DK) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010012650-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISEASES | SYDDANSK UNIVERSITET (DK) | 2010-02-04 | — | — | WO | disclosed |