Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAN1B1 | Q9UKM7 | 8/20 | 0.38 |
| ▸ | MAN2A1 | Q16706 | 7/20 | 0.38 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 4/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CERT1 | Q9Y5P4 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15574089 | 0.97 | OGA (0.40) | MAN1B1MAN2A1MAN2B1OGAGBA1 | |
| SCHEMBL15516920 | 0.91 | MAN1B1 (0.36) | MAN1B1MAN2A1MAN2B1OGAGBA1 | |
| SCHEMBL15517130 | 0.91 | MAN1B1 (0.36) | MAN1B1MAN2A1MAN2B1OGAGBA1 | |
| SCHEMBL15517022 | 0.91 | MAN1B1 (0.36) | MAN1B1MAN2A1MAN2B1OGAGBA1 | |
| SCHEMBL15517614 | 0.91 | MAN1B1 (0.36) | MAN1B1MAN2A1MAN2B1OGAGBA1 | |
| SCHEMBL15573973 | 0.87 | CERT1 (0.34) | MAN1B1MAN2A1MAN2B1CERT1MTNR1A | |
| SCHEMBL15574509 | 0.87 | CERT1 (0.34) | MAN1B1MAN2A1MAN2B1CERT1MTNR1A | |
| SCHEMBL15517028 | 0.87 | MAN1B1 (0.40) | MAN1B1MAN2A1MAN2B1OGAGBA1 | |
| SCHEMBL15574485 | 0.86 | OGA (0.53) | MAN1B1MAN2A1MAN2B1OGAMTNR1A | |
| SCHEMBL15573838 | 0.84 | MAN1B1 (0.41) | MAN1B1MAN2A1MAN2B1OGAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890678-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | Alectos Therapeutics Inc. (CA) | 2015-07-08 | — | — | EP | claimed |
| WO-2014032187-A1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | ALECTOS THERAPEUTICS INC. (CA) | 2014-03-06 | — | — | WO | claimed |