SCHEMBL1551732

SCHEMBL1551732

CC(C)N(CNP(O)O)C(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27477335 0.75 MEN1 (0.39) MEN1KMT2A
SCHEMBL29669513 0.67 MEN1 (0.38) MEN1KMT2A
SCHEMBL25594688 0.65 MEN1 (0.36) MEN1KMT2A
SCHEMBL991455 0.63
SCHEMBL19901608 0.61 MEN1 (0.33) MEN1KMT2A
SCHEMBL5822510 0.59 MEN1 (0.32) MEN1KMT2A
SCHEMBL9579552 0.59 MEN1 (0.36) MEN1KMT2A
SCHEMBL27929996 0.57 MEN1 (0.35) MEN1KMT2A
SCHEMBL11122660 0.57 MAPK1 (0.38) MEN1KMT2A
SCHEMBL7529812 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2376515-A1 Synthesis of purine nucleosides Pharmasset, Inc. (US) 2011-10-19 EP disclosed
EP-2313422-A2 NUCLEOSIDE CYCLICPHOSPHATES Pharmasset, Inc. (US) 2011-04-27 EP disclosed
WO-2010075554-A1 SYNTHESIS OF PURINE NUCLEOSIDES PHARMASSET, INC. (US) 2010-07-01 WO disclosed
WO-2009152095-A2 NUCLEOSIDE CYCLICPHOSPHATES PHARMASSET, INC. (US) 2009-12-17 WO disclosed
US-5969135-A COMPOUNDS FOR USE AS ANTISENSE CONTROL OF GENE EXPRESSION AND HYBRIDIZATION ICN PHARMACEUTICALS, INC. (US) 1999-10-19 US disclosed
EP-0789707-A4 AMINO ACID NUCLEIC ACIDS ICN PHARMACEUTICALS (US) 1999-02-24 EP disclosed
EP-0789707-A1 AMINO ACID NUCLEIC ACIDS ICN PHARMACEUTICALS (US) 1997-08-20 EP disclosed
EP-0416817-B1 Amplification processes ZENECA LTD (GB) 1996-10-16 EP disclosed
US-5525494-A Amplification processes ZENECA LIMITED (GB) 1996-06-11 US disclosed
WO-1996014330-A1 AMINO ACID NUCLEIC ACIDS ICNPHARMACEUTICALS (US) 1996-05-17 WO disclosed
EP-0416817-A2 Amplification processes ZENECA LIMITED (GB) 1991-03-13 EP disclosed