SCHEMBL1551765

SCHEMBL1551765

NC(=O)Oc1ccc2[nH]c(-c3ccc(OCCC4CCCCN4Cc4ccc(Cl)c(Cl)c4)cc3)nc2c1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHEK2 O96017 19/20 0.77
HCRTR1 O43613 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1552666 0.93 CHEK2 (0.76) CHEK2
SCHEMBL1551823 0.91 CHEK2 (0.89) CHEK2
SCHEMBL1552310 0.91 CHEK2 (0.76) CHEK2
SCHEMBL1551745 0.91 CHEK2 (0.76) CHEK2
SCHEMBL1552368 0.91 CHEK2 (0.75) CHEK2
SCHEMBL5640266 0.89 CHEK2 (0.78) CHEK2HCRTR1
SCHEMBL1552981 0.86 CHEK2 (0.76) CHEK2
SCHEMBL1551673 0.84 CHEK2 (0.88) CHEK2
SCHEMBL1552275 0.82 CHEK2 (0.89) CHEK2
SCHEMBL1552257 0.82 CHEK2 (0.89) CHEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1824832-B1 ARYL-SUBSTITUTED BENZIMIDAZOLE AND IMIDAZOPYRIDINE ETHERS AS ANTI-CANCER AGENTS JANSSEN PHARMACEUTICA NV (BE) 2011-04-27 EP claimed