Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347634 | 0.80 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL5632948 | 0.79 | TRPV1 (0.85) | TRPV1 | |
| SCHEMBL4200069 | 0.79 | TRPV1 (0.77) | TRPV1 | |
| SCHEMBL4192626 | 0.78 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4348270 | 0.77 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL5632131 | 0.76 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4197703 | 0.76 | TRPV1 (0.79) | TRPV1 | |
| SCHEMBL4347247 | 0.76 | TRPV1 (0.79) | TRPV1 | |
| SCHEMBL5632893 | 0.75 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL5632582 | 0.72 | TRPV1 (0.85) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673895-B2 | Tetrahydro-pyrimidoazepines as modulators of TRPV1 | JANSSEN PHARMACEUTICA NV (BE) | 2014-03-18 | — | — | US | disclosed |