Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 10/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 5/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23478503 | 0.78 | RXFP1 (0.41) | KMT2A | |
| SCHEMBL15520986 | 0.74 | BCHE (0.38) | ALDH1A1SMN1; SMN2KMT2ARORCACSS2 | |
| SCHEMBL16331628 | 0.73 | HPGD (0.50) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL23474006 | 0.70 | CYP3A4 (0.48) | SMN1; SMN2 | |
| SCHEMBL15519664 | 0.69 | RXFP1 (0.36) | ALDH1A1KMT2A | |
| SCHEMBL23479477 | 0.69 | RXFP1 (0.41) | — | |
| SCHEMBL30855433 | 0.68 | RXFP1 (0.42) | SMN1; SMN2 | |
| SCHEMBL29196668 | 0.68 | RXFP1 (0.42) | SMN1; SMN2 | |
| SCHEMBL16809631 | 0.68 | RHEB (0.46) | ALDH1A1KMT2ARORC | |
| SCHEMBL16795077 | 0.66 | RXFP1 (0.41) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014033497-A1 | 5-AZAINDOLE COMPOUNDS WITH ANTICANCER AND ANTIANGIOGENIC ACTIVITIES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-03-06 | — | — | WO | disclosed |