Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.62 |
| ▸ | TERT | O14746 | 3/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | TOP1 | P11387 | 3/20 | 0.56 |
| ▸ | F7 | P08709 | 3/20 | 0.56 |
| ▸ | F3 | P13726 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845712 | 0.93 | FASN (0.62) | FASNTERTPTPN1PPARGPPARD | |
| SCHEMBL28717330 | 0.90 | PPARG (0.67) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL28720538 | 0.90 | PPARG (0.67) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL28720631 | 0.90 | PPARG (0.67) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL4446343 | 0.90 | PPARG (0.67) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL28723581 | 0.90 | PPARG (0.67) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL7056891 | 0.90 | PPARG (0.67) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL28720496 | 0.90 | PPARG (0.67) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL28714312 | 0.90 | PPARG (0.67) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL28717421 | 0.90 | PPARG (0.67) | TERTPTPN1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014039964-A2 | COMPOUNDS AND METHODS FOR MODULATING VASCULAR INJURY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-03-13 | — | — | WO | disclosed |