Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 6/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764522 | 0.81 | PDE7A (0.46) | PDE7ACA12CA1CA2CA4 | |
| SCHEMBL17478594 | 0.79 | PDE7A (0.45) | PDE7ACA12CA1CA2CA4 | |
| SCHEMBL6221451 | 0.79 | AHR (0.54) | PDE7ACA12CA1CA2CA4 | |
| SCHEMBL10587563 | 0.79 | TYMS (0.38) | AHRPDK2PDK4RARBRARG | |
| SCHEMBL6221081 | 0.78 | PDK2 (0.58) | AHRPDK2PDK4RARBRARG | |
| SCHEMBL15135472 | 0.76 | RARB (0.36) | CA12CA1CA2CA4CA7 | |
| SCHEMBL3079489 | 0.76 | PDK2 (0.44) | AHRPDK2PDK4RARBRARG | |
| SCHEMBL9378647 | 0.74 | TDP1 (0.41) | TSHR | |
| SCHEMBL31117008 | 0.73 | PDK2 (0.61) | PDE7ACA12CA1CA2CA4 | |
| SCHEMBL17397785 | 0.73 | PDE7A (0.39) | PDE7ACA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582667-B1 | HETEROCYCLIC SUBSTITUTED METHOXYPHENYL DERIVATIVES WITH OXOGROUP, METHOD FOR PRODUCING SAME AND USE AS GPR40 RECEPTOR MODULATORS | SANOFI SA (FR) | 2014-03-19 | — | — | EP | disclosed |