SCHEMBL15519375 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	HCAR2	Q8TDS4	2/20	0.40

▸	HCRTR1	O43613	14/20	0.40

▸	HCRTR2	O43614	14/20	0.40

▸	KDM5A	P29375	2/20	0.37

▸	KDM4C	Q9H3R0	2/20	0.37

▸	KDM5B	Q9UGL1	2/20	0.37

▸	KDM4A	O75164	1/20	0.37

▸	KDM2B	Q8NHM5	1/20	0.33

▸	MET	P08581	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15518883	0.88	HCRTR1 (0.52)	HCAR2HCRTR1HCRTR2
SCHEMBL15519023	0.82	HCAR2 (0.43)	HCAR2HCRTR1HCRTR2KDM5AKDM4C
SCHEMBL15519415	0.81	HCRTR1 (0.44)	HCRTR1HCRTR2
SCHEMBL15519638	0.79	HCRTR2 (0.49)	HCRTR1HCRTR2
SCHEMBL15519855	0.78	HCRTR1 (0.41)	HCRTR1HCRTR2KDM5AKDM4CKDM5B
SCHEMBL15521906	0.76	HCRTR1 (0.44)	HCAR2HCRTR1HCRTR2KDM5AKDM4C
SCHEMBL15519480	0.76	HCRTR1 (0.55)	HCRTR1HCRTR2
SCHEMBL15520474	0.74	HCRTR1 (0.50)	HCAR2HCRTR1HCRTR2
SCHEMBL15519376	0.73	HCRTR1 (0.39)	HCAR2HCRTR1HCRTR2KDM5AKDM4C
SCHEMBL15519475	0.73	HCRTR1 (0.61)	HCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2708537-A1	HETEROAROMATIC RING DERIVATIVE	Taisho Pharmaceutical Co., Ltd. (JP)	2014-03-19	—	—	EP	disclosed