⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658084 | 1.00 | — | — | |
| SCHEMBL28760226 | 1.00 | — | — | |
| SCHEMBL31290747 | 0.92 | — | — | |
| Methane SCHEMBL17048141 | 0.89 | — | — | |
| SCHEMBL7106625 | 0.81 | — | — | |
| SCHEMBL24696380 | 0.72 | — | — | |
| SCHEMBL34465950 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL31219489 | 0.70 | — | — | |
| SCHEMBL22461798 | 0.70 | — | — | |
| SCHEMBL532209 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892900-A1 | PYRAZOLOPYRIMIDINE COMPOUNDS AS KINASE INHIBITORS | Principia Biopharma Inc. (US) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014039899-A1 | PYRAZOLOPYRIMIDINE COMPOUNDS AS KINASE INHIBITORS | PRINCIPIA BIOPHARMA INC. (US) | 2014-03-13 | — | — | WO | disclosed |