Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LTC4S | Q16873 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681076 | 0.90 | CETP (0.35) | KDM4ECCRL2L3MBTL1PTGDR2 | |
| SCHEMBL681075 | 0.90 | CETP (0.35) | KDM4ECCRL2L3MBTL1PTGDR2 | |
| SCHEMBL679434 | 0.90 | KDM4E (0.36) | KDM4ECCRL2CRHR1L3MBTL1PTGDR2 | |
| SCHEMBL679433 | 0.90 | KDM4E (0.36) | KDM4ECCRL2CRHR1L3MBTL1PTGDR2 | |
| SCHEMBL15519680 | 0.84 | PTGDR2 (0.34) | KDM4ECCRL2L3MBTL1PTGDR2LTC4S | |
| SCHEMBL15519681 | 0.84 | PTGDR2 (0.34) | KDM4ECCRL2L3MBTL1PTGDR2LTC4S | |
| SCHEMBL681081 | 0.82 | KDM4E (0.37) | KDM4ECRHR1L3MBTL1PTGDR2MEN1 | |
| SCHEMBL681080 | 0.82 | KDM4E (0.37) | KDM4ECRHR1L3MBTL1PTGDR2MEN1 | |
| SCHEMBL680412 | 0.81 | CETP (0.33) | PTGDR2 | |
| SCHEMBL680413 | 0.81 | CETP (0.33) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2383253-B1 | METHOD FOR MANUFACTURING TRANS-{4-[(ALKYL AMINO) METHYL]CYCLOHEXYL} ACETIC ESTER | KOWA CO (JP) | 2014-03-19 | — | — | EP | disclosed |