Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 5/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 3/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14053485 | 0.89 | TP53 (0.40) | TP53MAPTRORCPPARGPPARD | |
| SCHEMBL15519752 | 0.84 | MAPT (0.38) | TP53MAPTRORCPPARGPPARD | |
| SCHEMBL15519650 | 0.82 | PPARG (0.38) | TP53MAPTRORCPPARGPPARD | |
| SCHEMBL15519846 | 0.78 | TP53 (0.41) | TP53MAPTRORCPPARGPPARD | |
| SCHEMBL14054794 | 0.77 | TP53 (0.35) | TP53MAPTRORCPPARGPPARD | |
| SCHEMBL18299930 | 0.76 | TP53 (0.36) | TP53MAPTRORCPPARGPPARD | |
| SCHEMBL12096759 | 0.75 | PPARG (0.43) | TP53MAPTRORCPPARGPPARD | |
| SCHEMBL14054102 | 0.75 | MAPT (0.40) | TP53MAPTRORCPPARGPPARD | |
| SCHEMBL12096942 | 0.74 | PPARG (0.44) | TP53MAPTRORCPPARGPPARD | |
| SCHEMBL15519792 | 0.74 | PPARG (0.39) | TP53MAPTRORCPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |