Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 16/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 16/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519621 | 0.83 | HCRTR1 (0.43) | HCRTR1HCRTR2HCAR2 | |
| SCHEMBL15521906 | 0.82 | HCRTR1 (0.44) | HCRTR1HCRTR2HCAR2PDE10ANAMPT | |
| SCHEMBL15518972 | 0.80 | HCRTR1 (0.62) | HCRTR1HCRTR2 | |
| SCHEMBL15519023 | 0.78 | HCAR2 (0.43) | HCRTR1HCRTR2HCAR2PDE10ANAMPT | |
| SCHEMBL15519931 | 0.76 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL15519454 | 0.75 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL15519053 | 0.74 | HCRTR2 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL15519376 | 0.73 | HCRTR1 (0.39) | HCRTR1HCRTR2HCAR2NAMPTAR | |
| SCHEMBL15520474 | 0.72 | HCRTR1 (0.50) | HCRTR1HCRTR2HCAR2 | |
| SCHEMBL15519028 | 0.72 | HCRTR1 (0.62) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| EP-2708537-A1 | HETEROAROMATIC RING DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | HCRTR2, HCRTR1, HTT | HCRTR1 2/4885HCRTR2 1/4885HCAR2 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.