Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15327006 | 0.84 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL15326988 | 0.83 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL15327026 | 0.81 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL9977817 | 0.80 | HCRTR1 (0.50) | HCRTR1HCRTR2 | |
| SCHEMBL9977759 | 0.79 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL9977847 | 0.77 | HCRTR1 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL9977836 | 0.77 | HCRTR1 (0.73) | HCRTR1HCRTR2 | |
| SCHEMBL9977839 | 0.77 | HCRTR1 (0.75) | HCRTR1HCRTR2 | |
| SCHEMBL15520198 | 0.77 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL15521943 | 0.76 | HCRTR1 (0.48) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2708537-A1 | HETEROAROMATIC RING DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-03-19 | — | — | EP | disclosed |