Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 18/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 17/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13833187 | 0.88 | HCRTR1 (0.65) | HCRTR2HCRTR1 | |
| SCHEMBL15519358 | 0.87 | HCRTR1 (0.60) | HCRTR2HCRTR1PDE10A | |
| SCHEMBL15522063 | 0.83 | HCRTR1 (0.57) | HCRTR2HCRTR1 | |
| SCHEMBL15521964 | 0.81 | HCRTR1 (0.62) | HCRTR2HCRTR1 | |
| SCHEMBL15520879 | 0.81 | HCRTR1 (0.50) | HCRTR2HCRTR1PDE10A | |
| SCHEMBL16648787 | 0.77 | HCRTR1 (0.85) | HCRTR2HCRTR1 | |
| SCHEMBL15519053 | 0.76 | HCRTR2 (0.48) | HCRTR2HCRTR1 | |
| SCHEMBL15519484 | 0.74 | HCRTR1 (0.63) | HCRTR2HCRTR1PDE10A | |
| SCHEMBL15521960 | 0.74 | HCRTR1 (0.70) | HCRTR2HCRTR1 | |
| SCHEMBL13833377 | 0.73 | HCRTR1 (0.73) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
| EP-2708537-A1 | HETEROAROMATIC RING DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2014-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140081025-A1 | HETEROAROMATIC RING DERIVATIVE | HCRTR2, HCRTR1, HTT | HCRTR2 1/4885HCRTR1 2/4885PDE10A 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.