Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KLK7 | P49862 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15586040 | 0.93 | CYP4F2 (0.58) | CYP4F2CYP4A11FFAR1FFAR4HTT | |
| SCHEMBL15581448 | 0.88 | CYP4F2 (0.53) | CYP4F2CYP4A11FFAR1FFAR4ALDH1A1 | |
| SCHEMBL4578847 | 0.88 | FFAR1 (0.63) | CYP4F2CYP4A11FFAR1FFAR4HTT | |
| SCHEMBL15581420 | 0.88 | CYP4F2 (0.53) | CYP4F2CYP4A11FFAR1FFAR4HTT | |
| SCHEMBL15522776 | 0.82 | CYP4F2 (0.47) | CYP4F2CYP4A11FFAR1FFAR4HTT | |
| SCHEMBL7042002 | 0.81 | CYP4F2 (0.58) | CYP4F2CYP4A11FFAR1FFAR4HTT | |
| SCHEMBL313139 | 0.81 | HTT (0.69) | CYP4F2CYP4A11HTTALDH1A1F2RL1 | |
| SCHEMBL15522689 | 0.79 | CYP4F2 (0.64) | CYP4F2CYP4A11HTTALDH1A1F2RL1 | |
| SCHEMBL7421875 | 0.78 | CYP4F2 (0.62) | CYP4F2CYP4A11ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL4579260 | 0.78 | CYP4F2 (0.57) | CYP4F2CYP4A11FFAR1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140081017-A1 | Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents | METHYLGENE INC. (CA) | 2014-03-20 | — | — | US | disclosed |
| US-20140081017-A1 | Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents | METHYLGENE INC. (CA) | 2014-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140081017-A1 | Histone Deacetylase Inhibitors for Enhancing Activity of Antifungal Agents | HDAC1, HDAC5, HDAC7 | CYP4F2 2410/4885CYP4A11 840/4885FFAR1 2423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.