Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552745 | 0.94 | CHEK2 (0.75) | CHEK2 | |
| SCHEMBL1551654 | 0.93 | CHEK2 (0.75) | CHEK2 | |
| SCHEMBL1552763 | 0.92 | CHEK2 (0.74) | CHEK2 | |
| SCHEMBL1552714 | 0.92 | CHEK2 (0.74) | CHEK2 | |
| SCHEMBL1552981 | 0.91 | CHEK2 (0.76) | CHEK2 | |
| SCHEMBL1552256 | 0.91 | CHEK2 (0.88) | CHEK2 | |
| SCHEMBL5639438 | 0.88 | CHEK2 (0.76) | CHEK2DHODH | |
| SCHEMBL1552324 | 0.85 | CHEK2 (0.74) | CHEK2 | |
| SCHEMBL1552310 | 0.85 | CHEK2 (0.76) | CHEK2 | |
| SCHEMBL1551713 | 0.85 | CHEK2 (0.73) | CHEK2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824832-B1 | ARYL-SUBSTITUTED BENZIMIDAZOLE AND IMIDAZOPYRIDINE ETHERS AS ANTI-CANCER AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2011-04-27 | — | — | EP | claimed |