SCHEMBL15524360

SCHEMBL15524360

CCc1cc(O)cc(O)c1C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 0.76
PTPN11 Q06124 3/20 0.76
PTPN2 P17706 2/20 0.61
CYP3A4 P08684 5/20 0.59
ACHE P22303 1/20 0.59
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
PTGS1 P23219 1/20 0.55
DRD3 P35462 1/20 0.55
POLB P06746 1/20 0.55
PTGES O14684 2/20 0.54
TOP2A P11388 1/20 0.54
HPGD P15428 2/20 0.50
NR1H2 P55055 1/20 0.50
NR1H3 Q13133 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 1/20 0.45
ALOX15 P16050 1/20 0.45
MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27816563 0.89 PTPN1 (0.60) PTPN1PTPN11PTPN2CYP3A4ACHE
SCHEMBL2559667 0.86 PTPN1 (1.00) PTPN1PTPN11PTPN2CYP3A4ACHE
SCHEMBL29424249 0.86 PTPN1 (1.00) PTPN1PTPN11PTPN2CYP3A4ACHE
SCHEMBL18677517 0.83 PTPN1 (0.81) PTPN1PTPN11PTPN2CYP3A4ACHE
SCHEMBL30261073 0.83 PTPN1 (0.81) PTPN1PTPN11PTPN2CYP3A4ACHE
SCHEMBL15782810 0.83 MEN1 (0.70) PTPN1PTPN11PTPN2CYP3A4ACHE
SCHEMBL28253661 0.82 PTPN1 (0.64) PTPN1PTPN11PTPN2CYP3A4ACHE
SCHEMBL9909323 0.82 PTPN1 (0.78) PTPN1PTPN11PTPN2PTGESTOP2A
SCHEMBL29367141 0.82 PTPN1 (0.78) PTPN1PTPN11PTPN2PTGESTOP2A
SCHEMBL21383336 0.82 PTPN1 (0.82) PTPN1PTPN11PTPN2CYP3A4ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230029027-A1 COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ENZYMES RENEW BIOPHARMA, INC. 2023-01-26 US claimed
WO-2020210810-A9 COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ENZYMES RENEW BIOPHARMA, INC. (US) 2020-11-26 WO claimed
WO-2020210810-A1 COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ENZYMES RENEW BIOPHARMA, INC. (US) 2020-10-15 WO claimed
WO-2019183152-A1 COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ENZYMES RENEW BIOPHARMA, INC. (US) 2019-09-26 WO claimed
US-12540315-B2 Compositions and methods for using genetically modified enzymes RENEW BIOPHARMA, INC. (US) 2026-02-03 US disclosed
US-20250188050-A1 RECOMBINANT POLYPEPTIDES WITH BERBERINE BRIDGE ENZYME ACTIVITY USEFUL FOR THE BIOSYNTHESIS OF CANNABINOIDS INVIZYNE TECHNOLOGIES, INC. (US) 2025-06-12 US disclosed
US-20250043319-A1 BIOSYNTHESIS OF CYCLOLAVANDULYL DERIVATIVES OF AROMATIC COMPOUNDS INVIZYNE TECHNOLOGIES, INC. (US) 2025-02-06 US disclosed
US-12084689-B2 Prenyltransferase variants with increased thermostability INVIZYNE TECHNOLOGIES, INC. (US) 2024-09-10 US disclosed
WO-2023205404-A2 BIOSYNTHESIS OF CYCLOLAVANDULYL DERIVATIVES OF AROMATIC COMPOUNDS INVIZYNE TECHNOLOGIES, INC. (US) 2023-10-26 WO disclosed
WO-2023133483-A1 RECOMBINANT POLYPEPTIDES WITH BERBERINE BRIDGE ENZYME ACTIVITY USEFUL FOR THE BIOSYNTHESIS OF CANNABINOIDS INVIZYNE TECHNOLOGIES, INC. (US) 2023-07-13 WO disclosed
US-20230098978-A1 PRENYLTRANSFERASE VARIANTS WITH INCREASED THERMOSTABILITY INVIZYNE TECHNOLOGIES, INC. (US) 2023-03-30 US disclosed
US-20230029027-A1 COMPOSITIONS AND METHODS FOR USING GENETICALLY MODIFIED ENZYMES RENEW BIOPHARMA, INC. 2023-01-26 US disclosed
WO-2017051020-A1 DYE COMPOSITION COMPRISING A RESORCINOL-BASED COUPLER AND AN OXIDATION BASE L'OREAL (FR) 2017-03-30 WO disclosed
CN-102115757-B Platform hooks biological synthesis gene cluster and the application thereof of mycin SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY, CHINESE ACADEMY OF SCIENCES (CN) 2015-10-28 CN disclosed
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed
CN-101817745-B Chemical synthesis method of 3,5-dichloro-4-hydroxy-2-methoxy-6-methyl-benzoic acid UNIV HUAZHONG AGRICULTURAL 2013-03-13 CN disclosed
CN-101817745-A Chemical synthesis method of 3,5-dichloro-4-hydroxy-2-methoxy-6-methyl-benzoic acid UNIV HUAZHONG AGRICULTURAL 2010-09-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540315-B2 Compositions and methods for using genetically modified enzymes COASY, CYP4F3, CYP4F11 PTPN1 2972/4885PTPN11 3207/4885PTPN2 3676/4885
US-20250188050-A1 RECOMBINANT POLYPEPTIDES WITH BERBERINE BRIDGE ENZYME ACTIVITY USEFUL FOR THE BIOSYNTHESIS OF CANNABINOIDS COASY, CBR1, CBR3 PTPN1 4410/4885PTPN11 4428/4885PTPN2 4318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.