Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 14/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 14/20 | 0.49 |
| ▸ | JAK2 | O60674 | 13/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15524509 | 0.92 | STAT6 (0.45) | JAK3PTK2JAK2ALKIGF1R | |
| SCHEMBL12479394 | 0.91 | PTK2 (0.48) | JAK3PTK2JAK2NAMPTIGF1R | |
| SCHEMBL14576442 | 0.87 | PTK2 (0.45) | JAK3PTK2JAK2 | |
| SCHEMBL14635977 | 0.85 | ALK (0.56) | PTK2ALK | |
| SCHEMBL15524430 | 0.84 | STAT6 (0.46) | JAK3PTK2JAK2ALKNAMPT | |
| SCHEMBL14577154 | 0.84 | PTK2 (0.52) | JAK3PTK2JAK2STAT6 | |
| SCHEMBL15524357 | 0.84 | PTK2 (0.47) | JAK3PTK2JAK2ALKIGF1R | |
| SCHEMBL15524207 | 0.84 | PTK2 (0.51) | JAK3PTK2JAK2ALKIGF1R | |
| SCHEMBL15524399 | 0.84 | PTK2 (0.47) | JAK3PTK2JAK2ALKIGF1R | |
| SCHEMBL15524511 | 0.84 | PTK2 (0.41) | JAK3PTK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266864-B2 | VEGFR3 inhibitors | CANCER THERAPEUTICS CRC PTY LIMITED (AU) | 2016-02-23 | — | — | US | disclosed |
| US-20150225377-A1 | VEGFR3 INHIBITORS | CANCER THERAPEUTICS CRC PTY LIMITED (AU) | 2015-08-13 | — | — | US | disclosed |
| US-20140080798-A1 | VEGFR3 INHIBITORS | CANCER THERAPEUTICS CRC PTY LIMITED (AU) | 2014-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225377-A1 | VEGFR3 INHIBITORS | FLT4, FLT1, KDR | JAK3 26/4885PTK2 240/4885JAK2 143/4885 |
| US-20140080798-A1 | VEGFR3 INHIBITORS | FLT4, FLT1, KDR | JAK3 26/4885PTK2 260/4885JAK2 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.