Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
| ▸ | RELA | Q04206 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889569 | 0.82 | SKP2 (0.47) | SKP2HTR2ADRD2SLC6A2HTR2C | |
| SCHEMBL28895060 | 0.80 | NPC1 (0.49) | SKP2HTR2ADRD2SLC6A2HTR2C | |
| SCHEMBL2930325 | 0.77 | HTR2A (0.52) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL31228811 | 0.77 | HTR2A (0.52) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL4900272 | 0.76 | HTR2A (0.55) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL4895814 | 0.76 | HTR2A (0.55) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL4898274 | 0.76 | HTR2A (0.55) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL4887234 | 0.76 | HTR2A (0.55) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL30369240 | 0.76 | HTR2A (0.55) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL4946924 | 0.76 | HTR2A (0.46) | SKP2HTR2ADRD2SLC6A2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838929-A1 | POLYMERS CONTAINING SUBSTITUTED TRIARYLAMINE UNITS AND ELECTROLUMINESCENT DEVICES CONTAINING SAID POLYMERS | Merck Patent GmbH (DE) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013156130-A1 | POLYMERS CONTAINING SUBSTITUTED TRIARYLAMINE UNITS AND ELECTROLUMINESCENT DEVICES CONTAINING SAID POLYMERS | MERCK PATENT GMBH (DE) | 2013-10-24 | — | — | WO | disclosed |