Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | BMX | P51813 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15525467 | 0.85 | BTK (0.62) | BTK | |
| SCHEMBL15525491 | 0.85 | BTK (0.85) | BTK | |
| SCHEMBL15607785 | 0.83 | BTK (0.74) | BTK | |
| SCHEMBL15525964 | 0.82 | BTK (0.60) | BTK | |
| SCHEMBL15525543 | 0.82 | BTK (0.69) | BTK | |
| SCHEMBL15610821 | 0.82 | BTK (0.58) | BTK | |
| SCHEMBL15525487 | 0.82 | BTK (0.64) | BTK | |
| SCHEMBL15526072 | 0.80 | BTK (0.61) | BTK | |
| SCHEMBL15525544 | 0.80 | BTK (0.65) | BTK | |
| SCHEMBL15525585 | 0.79 | BTK (0.87) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013157021-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | ADVINUS THERAPEUTICS LIMITED (IN) | 2013-10-24 | — | — | WO | claimed |