Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 20/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 19/20 | 0.56 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.46 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22354644 | 0.93 | HSP90AB1 (0.65) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL15525975 | 0.92 | HSP90AA1 (0.59) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL2814577 | 0.90 | HSP90AB1 (0.59) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL15613142 | 0.89 | HSP90AB1 (0.53) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL501023 | 0.88 | HSP90AB1 (0.52) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL501271 | 0.87 | HSP90AB1 (0.51) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL501442 | 0.85 | HSP90AA1 (0.62) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL18096418 | 0.85 | HSP90AA1 (0.59) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL10233626 | 0.84 | HSP90AB1 (0.48) | HSP90AB1HSP90AA1HSP90B1TRAP1 | |
| SCHEMBL15526014 | 0.84 | HSP90AB1 (0.55) | HSP90AB1HSP90AA1HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838909-A2 | TARGETED THERAPEUTICS | Synta Pharmaceuticals Corp. (US) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013158644-A2 | TARGETED THERAPEUTICS | SYNTA PHARMACEUTICALS CORP. (US) | 2013-10-24 | — | — | WO | disclosed |