Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | LIPC | P11150 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15332331 | 0.88 | EIF4E (0.38) | EIF4ETP53MAPTLMNADHODH | |
| SCHEMBL15333045 | 0.88 | EIF4E (0.38) | EIF4ETP53MAPTLMNADHODH | |
| SCHEMBL15342045 | 0.85 | EIF4E (0.37) | EIF4ETP53MAPTLMNADHODH | |
| SCHEMBL15342417 | 0.84 | EIF4E (0.35) | EIF4ETP53MAPTLMNARXFP1 | |
| SCHEMBL15526380 | 0.83 | MAPT (0.33) | MAPTRXFP1 | |
| SCHEMBL15526437 | 0.83 | EIF4E (0.35) | EIF4ETP53MAPTLMNARXFP1 | |
| SCHEMBL17547091 | 0.82 | EIF4E (0.41) | EIF4ETP53MAPTLMNADHODH | |
| SCHEMBL15526305 | 0.81 | MAPT (0.35) | MAPTRXFP1DHODHRARB | |
| SCHEMBL15526260 | 0.81 | MAPT (0.32) | MAPTRXFP1 | |
| SCHEMBL15526216 | 0.81 | MAPT (0.39) | TP53MAPTLMNARXFP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788336-A1 | BENZOTHIAZOL- 6 -YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | Gilead Sciences, Inc. (US) | 2014-10-15 | — | — | EP | disclosed |
| WO-2013159064-A1 | BENZOTHIAZOL- 6 -YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES, INC. (US) | 2013-10-24 | — | — | WO | disclosed |