Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15527791 | 0.77 | GAA (0.32) | ALDH1A1GSTP1GSTM2MAPTLMNA | |
| SCHEMBL9299013 | 0.70 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6PRMT1ALDH1A1 | |
| SCHEMBL9068773 | 0.69 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2D6PRMT1ALDH1A1 | |
| SCHEMBL5983521 | 0.68 | MAPK1 (0.36) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL11192730 | 0.68 | MEN1 (0.42) | CYP1A2CYP3A4CYP2D6PRMT1ALDH1A1 | |
| SCHEMBL9712288 | 0.66 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2D6PRMT1ALDH1A1 | |
| SCHEMBL7270524 | 0.66 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2D6PRMT1ALDH1A1 | |
| SCHEMBL3701096 | 0.66 | MEN1 (0.45) | CYP1A2CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL2668682 | 0.66 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2D6PRMT1ALDH1A1 | |
| SCHEMBL5680420 | 0.65 | CYP2D6 (0.63) | CYP1A2CYP3A4CYP2D6PRMT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013166466-A1 | HOT-START DIGITAL PCR | BIO-RAD LABORATORIES, INC. (US) | 2013-11-07 | — | — | WO | disclosed |