SCHEMBL15529043

SCHEMBL15529043

COCc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15528928 0.84 RXFP1 (1.00) RXFP1
SCHEMBL15528748 0.84 RXFP1 (1.00) RXFP1
SCHEMBL15529123 0.83 RXFP1 (1.00) RXFP1
SCHEMBL15528828 0.82 RXFP1 (1.00) RXFP1
SCHEMBL15528909 0.82 RXFP1 (1.00) RXFP1
SCHEMBL15530435 0.82 RXFP1 (1.00) RXFP1
SCHEMBL15530140 0.82 RXFP1 (0.75) RXFP1
SCHEMBL15530607 0.81 RXFP1 (1.00) RXFP1
SCHEMBL15529153 0.81 RXFP1 (1.00) RXFP1
SCHEMBL15529235 0.81 RXFP1 (1.00) RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2844345-A1 MODULATORS OF THE RELAXIN RECEPTOR 1 The United States of America, as Represented by The Secretary, Department of Health and Human Services (US) 2015-03-11 EP disclosed
WO-2013165606-A1 MODULATORS OF THE RELAXIN RECEPTOR 1 THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2013-11-07 WO disclosed