Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15529197 | 1.00 | NAMPT (0.71) | NAMPT | |
| SCHEMBL15528746 | 0.93 | NAMPT (0.61) | NAMPT | |
| SCHEMBL15529140 | 0.93 | NAMPT (0.61) | NAMPT | |
| SCHEMBL15529469 | 0.93 | NAMPT (0.61) | NAMPT | |
| SCHEMBL15528955 | 0.92 | NAMPT (0.60) | NAMPT | |
| SCHEMBL15529766 | 0.91 | NAMPT (0.58) | NAMPT | |
| SCHEMBL16228303 | 0.89 | NAMPT (0.66) | NAMPT | |
| SCHEMBL15528888 | 0.89 | NAMPT (0.70) | NAMPT | |
| SCHEMBL15529204 | 0.89 | NAMPT (0.66) | NAMPT | |
| SCHEMBL15528791 | 0.89 | NAMPT (0.66) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852585-A1 | NAMPT INHIBITORS | AbbVie Inc. (US) | 2015-04-01 | — | — | EP | claimed |
| WO-2013170113-A1 | NAMPT INHIBITORS | ABBVIE INC. (US) | 2013-11-14 | — | — | WO | claimed |
| EP-2852585-A1 | NAMPT INHIBITORS | AbbVie Inc. (US) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013170113-A1 | NAMPT INHIBITORS | ABBVIE INC. (US) | 2013-11-14 | — | — | WO | disclosed |