Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30167647 | 0.85 | NAMPT (0.82) | NAMPTCYP2C9 | |
| SCHEMBL174292 | 0.85 | NAMPT (0.82) | NAMPTCYP2C9 | |
| SCHEMBL161120 | 0.79 | NAMPT (0.69) | NAMPTCYP2C9 | |
| SCHEMBL15243583 | 0.77 | NAMPT (0.81) | NAMPT | |
| SCHEMBL12468038 | 0.77 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL30167609 | 0.77 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL16108063 | 0.77 | NAMPT (0.70) | NAMPTCYP2C9 | |
| SCHEMBL16108010 | 0.75 | NAMPT (0.69) | NAMPT | |
| SCHEMBL30167581 | 0.74 | NAMPT (1.00) | NAMPT | |
| SCHEMBL173594 | 0.74 | NAMPT (1.00) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013170191-A1 | METHODS OF USING ANTAGONISTS OF NAD BIOSYNTHESIS FROM NICOTINAMIDE | GENENTECH, INC. (US) | 2013-11-14 | — | — | WO | disclosed |