Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16108144 | 0.91 | NAMPT (0.69) | NAMPTCYP2C9 | |
| SCHEMBL159970 | 0.90 | NAMPT (0.66) | NAMPTCYP2C9 | |
| SCHEMBL12467001 | 0.89 | NAMPT (0.62) | NAMPTCYP2C9 | |
| SCHEMBL161559 | 0.87 | NAMPT (0.71) | NAMPTCYP2C9 | |
| SCHEMBL16107973 | 0.84 | NAMPT (0.62) | NAMPTCYP2C9 | |
| SCHEMBL12467941 | 0.84 | NAMPT (0.66) | NAMPTCYP2C9 | |
| SCHEMBL12468058 | 0.84 | NAMPT (0.70) | NAMPTCYP2C9 | |
| SCHEMBL174352 | 0.82 | NAMPT (0.68) | NAMPTCYP2C9 | |
| SCHEMBL171482 | 0.81 | NAMPT (0.67) | NAMPTCYP2C9 | |
| SCHEMBL173958 | 0.81 | NAMPT (0.75) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013170191-A1 | METHODS OF USING ANTAGONISTS OF NAD BIOSYNTHESIS FROM NICOTINAMIDE | GENENTECH, INC. (US) | 2013-11-14 | — | — | WO | disclosed |