Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 17/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15530163 | 0.92 | NAMPT (0.58) | NAMPTCYP2C9MEN1KMT2APOLB | |
| SCHEMBL15530688 | 0.89 | NAMPT (0.65) | NAMPTPOLB | |
| SCHEMBL15530177 | 0.89 | NAMPT (0.71) | NAMPTCYP2C9 | |
| SCHEMBL15530536 | 0.88 | NAMPT (0.67) | NAMPTPOLB | |
| SCHEMBL15531121 | 0.85 | NAMPT (0.70) | NAMPTPOLB | |
| SCHEMBL15530551 | 0.84 | NAMPT (0.74) | NAMPT | |
| SCHEMBL15530430 | 0.84 | NAMPT (0.61) | NAMPTCYP2C9 | |
| SCHEMBL15530664 | 0.84 | NAMPT (0.72) | NAMPTCYP2C9 | |
| SCHEMBL10290830 | 0.83 | POLB (0.71) | NAMPTCYP2C9MEN1KMT2APOLB | |
| SCHEMBL15529861 | 0.83 | NAMPT (0.83) | NAMPTCYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013170191-A1 | METHODS OF USING ANTAGONISTS OF NAD BIOSYNTHESIS FROM NICOTINAMIDE | GENENTECH, INC. (US) | 2013-11-14 | — | — | WO | disclosed |