Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 17/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30167786 | 0.82 | NAMPT (1.00) | NAMPT | |
| SCHEMBL15530852 | 0.82 | NAMPT (1.00) | NAMPT | |
| SCHEMBL15246525 | 0.80 | HDAC3 (0.52) | NAMPTHDAC1HDAC2HDAC3 | |
| SCHEMBL15531666 | 0.77 | NAMPT (0.69) | NAMPTHDAC1HDAC2HDAC3NCOR2 | |
| SCHEMBL10280400 | 0.74 | NAMPT (1.00) | NAMPT | |
| SCHEMBL30167834 | 0.74 | NAMPT (1.00) | NAMPT | |
| SCHEMBL15530688 | 0.74 | NAMPT (0.65) | NAMPT | |
| SCHEMBL15530536 | 0.71 | NAMPT (0.67) | NAMPT | |
| SCHEMBL15246259 | 0.71 | NAMPT (0.68) | NAMPT | |
| SCHEMBL15246210 | 0.71 | NAMPT (0.61) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013170191-A1 | METHODS OF USING ANTAGONISTS OF NAD BIOSYNTHESIS FROM NICOTINAMIDE | GENENTECH, INC. (US) | 2013-11-14 | — | — | WO | disclosed |