Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16858017 | 0.92 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL16820363 | 0.90 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL16820508 | 0.90 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL16858024 | 0.88 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL16858060 | 0.86 | NAMPT (0.88) | NAMPTCYP2C9 | |
| SCHEMBL16858127 | 0.84 | NAMPT (0.88) | NAMPTCYP2C9 | |
| SCHEMBL16858090 | 0.83 | NAMPT (0.87) | NAMPTCYP2C9 | |
| SCHEMBL15246420 | 0.83 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL15529988 | 0.82 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL15243625 | 0.81 | NAMPT (1.00) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013170191-A1 | METHODS OF USING ANTAGONISTS OF NAD BIOSYNTHESIS FROM NICOTINAMIDE | GENENTECH, INC. (US) | 2013-11-14 | — | — | WO | disclosed |