Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15531879 | 0.96 | HPRT1 (0.47) | HPRT1 | |
| SCHEMBL16618127 | 0.92 | HPRT1 (0.50) | HPRT1 | |
| SCHEMBL15547073 | 0.89 | HPRT1 (0.65) | HPRT1 | |
| SCHEMBL15532234 | 0.88 | HPRT1 (0.54) | HPRT1 | |
| SCHEMBL15532441 | 0.88 | HPRT1 (0.51) | HPRT1 | |
| SCHEMBL16617658 | 0.86 | HPRT1 (0.59) | HPRT1 | |
| SCHEMBL16618146 | 0.86 | HPRT1 (0.59) | HPRT1 | |
| SCHEMBL15532664 | 0.85 | HPRT1 (0.67) | HPRT1 | |
| SCHEMBL15531924 | 0.84 | HPRT1 (0.72) | HPRT1 | |
| SCHEMBL15537667 | 0.84 | HPRT1 (0.40) | HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2847201-B1 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | UNIV QUEENSLAND (AU) | 2017-08-16 | — | — | EP | disclosed |
| US-9200020-B2 | 6-oxopurine phosphoribosyltransferase inhibitors | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-12-01 | — | — | US | disclosed |
| US-20150099722-A1 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2015-04-09 | — | — | US | disclosed |
| EP-2847201-A2 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | The University of Queensland (AU) | 2015-03-18 | — | — | EP | disclosed |
| WO-2013166545-A2 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2013-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099722-A1 | 6-OXOPURINE PHOSPHORIBOSYLTRANSFERASE INHIBITORS | HPRT1, APRT, TPMT | HPRT1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.