Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 19/20 | 0.71 |
| ▸ | EGFR | P00533 | 5/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | FECH | P22830 | 1/20 | 0.43 |
| ▸ | MYH14 | Q7Z406 | 1/20 | 0.43 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21563379 | 0.90 | ERBB2 (0.70) | ERBB2EGFRKCNH2 | |
| SCHEMBL30097878 | 0.86 | ERBB2 (0.67) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL4064521 | 0.84 | ERBB2 (0.59) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL21551347 | 0.84 | ERBB2 (1.00) | ERBB2EGFR | |
| SCHEMBL21563125 | 0.81 | ERBB2 (0.66) | ERBB2EGFR | |
| SCHEMBL24569699 | 0.81 | ERBB2 (0.59) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL20780984 | 0.81 | ERBB2 (0.59) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL29887942 | 0.81 | ERBB2 (0.59) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL24569501 | 0.80 | ERBB2 (0.58) | ERBB2EGFRNQO2FECHMYH14 | |
| SCHEMBL12873124 | 0.80 | ERBB2 (0.58) | ERBB2EGFRNQO2FECHMYH14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2090575-B1 | Processes and intermediates for the preparation of N4-phenyl-quinazoline-4-amine derivatives | ARRAY BIOPHARMA INC (US) | 2011-04-27 | — | — | EP | disclosed |