SCHEMBL15533482

SCHEMBL15533482

CC1CNCCC1(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24096592 1.00
Hydrochloric Acid SCHEMBL22119566 0.97 HTR2C (0.30)
SCHEMBL25055600 0.85
SCHEMBL14654797 0.77
SCHEMBL24593000 0.75
SCHEMBL23767906 0.75
SCHEMBL21649852 0.75
SCHEMBL17786319 0.75
SCHEMBL20683938 0.74
SCHEMBL14084275 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013177292-A1 TITANIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2013-11-28 WO claimed
WO-2013177284-A1 HAFNIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2013-11-28 WO claimed
WO-2013177269-A2 ZIRCONIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2013-11-28 WO claimed
US-12540129-B2 KIF18A inhibitors AMGEN INC. (US) 2026-02-03 US disclosed
US-12441736-B2 KIF18A inhibitors AMGEN INC. (US) 2025-10-14 US disclosed
EP-3898592-B1 HETEROARYL AMIDES USEFUL AS KIF18A INHIBITORS AMGEN INC (US) 2024-10-09 EP disclosed
US-20220372018-A1 KIF18A INHIBITORS AMGEN INC. (US) 2022-11-24 US disclosed
EP-4007638-A1 PYRIDINE DERIVATIVES AS KIF18A INHIBITORS Amgen Inc. (US) 2022-06-08 EP disclosed
CN-114391012-A Pyridine derivatives as KIF18A inhibitors 美国安进公司 2022-04-22 CN disclosed
US-20220002311-A1 KIF18A INHIBITORS AMGEN INC. (US) 2022-01-06 US disclosed
EP-3919496-A1 POLYCYCLIC COMPOUND INHIBITING MNK1 AND MNK2 Novostar Pharmaceuticals, Ltd. (CN) 2021-12-08 EP disclosed
EP-3898592-A1 HETEROARYL AMIDES USEFUL AS KIF18A INHIBITORS Amgen Inc. (US) 2021-10-27 EP disclosed
WO-2021026100-A1 PYRIDINE DERIVATIVES AS KIF18A INHIBITORS AMGEN INC. (US) 2021-02-11 WO disclosed
WO-2020155842-A1 POLYCYCLIC COMPOUND INHIBITING MNK1 AND MNK2 诺沃斯达药业有限公司 2020-08-06 WO disclosed
WO-2020132653-A1 HETEROARYL AMIDES USEFUL AS KIF18A INHIBITORS AMGEN INC. (US) 2020-06-25 WO disclosed
WO-2013177269-A2 ZIRCONIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2013-11-28 WO disclosed
WO-2013177284-A1 HAFNIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2013-11-28 WO disclosed
WO-2013177292-A1 TITANIUM-CONTAINING PRECURSORS FOR VAPOR DEPOSITION L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 2013-11-28 WO disclosed