Octadecanoic Acid Amide

Octadecanoic Acid Amide

SCHEMBL15533985

CC(C)O.CC(C)O.CCCCCCCCCCCCCCCCCC(N)=O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 2/20 0.63
MEN1 O00255 1/20 0.63
FAAH O00519 1/20 0.63
TP53 P04637 1/20 0.63
CYP1A2 P05177 1/20 0.63
CYP3A4 P08684 1/20 0.63
CYP2C19 P33261 1/20 0.63
KMT2A Q03164 1/20 0.63
KDM4E B2RXH2 2/20 0.57
CES2 O00748 3/20 0.54
CES1 P23141 3/20 0.54
GPR84 Q9NQS5 2/20 0.52
PPARG P37231 2/20 0.52
PPARD Q03181 2/20 0.52
PPARA Q07869 2/20 0.52
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
SLC22A8 Q8TCC7 1/20 0.52
TLR2 O60603 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL9626247 0.90 SOAT1 (0.74) SOAT1MEN1FAAHTP53CYP1A2
SCHEMBL2048989 0.90 SOAT1 (0.74) SOAT1MEN1FAAHTP53CYP1A2
SCHEMBL218192 0.90 SOAT1 (0.74) SOAT1MEN1FAAHTP53CYP1A2
SCHEMBL104521 0.90 SOAT1 (0.74) SOAT1MEN1FAAHTP53CYP1A2
Palmitamide SCHEMBL43384 0.90 SOAT1 (0.74) SOAT1MEN1FAAHTP53CYP1A2
Octadecanoic Acid Amide SCHEMBL8417300 0.90 SOAT1 (0.74) SOAT1MEN1FAAHTP53CYP1A2
SCHEMBL8743286 0.90 SOAT1 (0.74) SOAT1MEN1FAAHTP53CYP1A2
SCHEMBL42192 0.90 SOAT1 (0.74) SOAT1MEN1FAAHTP53CYP1A2
SCHEMBL22319678 0.90 SOAT1 (0.74) SOAT1MEN1FAAHTP53CYP1A2
SCHEMBL6046254 0.90 SOAT1 (0.74) SOAT1MEN1FAAHTP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10072230-B2 Method for reducing engine wear with lubricants comprising 2-hydroxyalkylamide friction modifying/anti-wear compositions CHEMTURA CORP (US) 2018-09-11 US disclosed
US-9562207-B2 Lubricants comprising 2-hydroxyalkylamide friction modifying compositions CHEMTURA CORPORATION (US) 2017-02-07 US disclosed
US-20160251591-A1 METHOD FOR REDUCING ENGINE WEAR WITH LUBRICANTS COMPRISING 2-HYDROXYALKYLAMIDE FRICTION MODIFYING / ANTI-WEAR COMPOSITIONS CHEMTURA CORP (US) 2016-09-01 US disclosed
US-20150376537-A1 Lubricants Comprising 2-Hydroxyalkylamide Friction Modifying Compositions CHEMTURA CORPORATION (US) 2015-12-31 US disclosed
EP-2852658-A1 LUBRICANTS COMPRISING 2-HYDROXYALKYLAMIDE FRICTION MODIFYING COMPOSITIONS Chemtura Corporation (US) 2015-04-01 EP disclosed
WO-2013176802-A1 LUBRICANTS COMPRISING 2-HYDROXYALKYLAMIDE FRICTION MODIFYING COMPOSITIONS CHEMTURA CORPORATION (US) 2013-11-28 WO disclosed