SCHEMBL15534665

SCHEMBL15534665

CC(C)(C)N1CCN(Cc2ccc(C(=O)Nc3sc(Nc4ccc5ccccc5c4)nc3C(N)=O)cc2)CC1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TNIK Q9UKE5 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16707055 0.92 TNIK (1.00) TNIK
SCHEMBL16699563 0.89 TNIK (1.00) TNIK
SCHEMBL15558152 0.89 TNIK (0.83) TNIK
SCHEMBL16701219 0.89 TNIK (0.78) TNIK
SCHEMBL16699335 0.89 TNIK (0.83) TNIK
SCHEMBL16707043 0.89 TNIK (1.00) TNIK
SCHEMBL15557322 0.88 TNIK (0.84) TNIK
SCHEMBL16700160 0.88 TNIK (1.00) TNIK
SCHEMBL16699706 0.88 TNIK (1.00) TNIK
SCHEMBL16699677 0.88 TNIK (1.00) TNIK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2855470-A1 NOVEL BICYCLIC THIAZOLE COMPOUNDS Carna Biosciences Inc. (JP) 2015-04-08 EP disclosed
WO-2013176293-A1 NOVEL BICYCLIC THIAZOLE COMPOUNDS CARNA BIOSCIENCES, INC. (JP) 2013-11-28 WO disclosed