Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 17/20 | 0.54 |
| ▸ | SCN7A | Q01118 | 3/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.54 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21825393 | 0.92 | SCN9A (0.56) | SCN9ASCN7ASCN5ARBP4 | |
| SCHEMBL15536406 | 0.88 | SCN9A (0.70) | SCN9ASCN7ASCN5A | |
| SCHEMBL16759164 | 0.87 | SCN9A (0.61) | SCN9ASCN7ASCN5A | |
| SCHEMBL15536836 | 0.86 | SCN9A (0.52) | SCN9ASCN7ASCN5A | |
| SCHEMBL15535893 | 0.82 | SCN9A (0.79) | SCN9ASCN7ASCN5A | |
| SCHEMBL16759392 | 0.82 | SCN9A (0.61) | SCN9ASCN7ASCN5A | |
| SCHEMBL16759218 | 0.81 | SCN9A (0.51) | SCN9ASCN5ARBP4 | |
| SCHEMBL17062754 | 0.81 | SCN9A (0.61) | SCN9ASCN7ASCN5A | |
| SCHEMBL16759224 | 0.81 | SCN9A (0.61) | SCN9ASCN7ASCN5A | |
| SCHEMBL16758978 | 0.80 | SCN7A (0.56) | SCN9ASCN7ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793238-B | Substituted benzamides and methods of use thereof | 基因泰克公司 | 2019-12-24 | — | — | CN | disclosed |
| EP-2855428-A1 | N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN | Genentech, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013177224-A1 | N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN | GENENTECH, INC. (US) | 2013-11-28 | — | — | WO | disclosed |