Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15536873 | 0.85 | SCN9A (0.72) | SCN9A | |
| SCHEMBL16449085 | 0.84 | SCN9A (0.59) | SCN9A | |
| Methane SCHEMBL16990456 | 0.84 | SCN9A (0.61) | SCN9A | |
| SCHEMBL16448613 | 0.83 | SCN9A (0.63) | SCN9A | |
| SCHEMBL15536696 | 0.82 | SCN9A (0.74) | SCN9A | |
| SCHEMBL15549710 | 0.82 | SCN9A (0.74) | SCN9A | |
| SCHEMBL16448640 | 0.82 | SCN9A (0.74) | SCN9A | |
| SCHEMBL15549708 | 0.82 | SCN9A (0.74) | SCN9A | |
| SCHEMBL16448641 | 0.82 | SCN9A (0.74) | SCN9A | |
| SCHEMBL17423075 | 0.82 | SCN9A (0.69) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855428-A1 | N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN | Genentech, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013177224-A1 | N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN | GENENTECH, INC. (US) | 2013-11-28 | — | — | WO | disclosed |