Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.56 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30261423 | 0.89 | SCN9A (0.61) | SCN9ASCN5A | |
| SCHEMBL15535642 | 0.88 | SCN9A (0.70) | SCN9ASCN5A | |
| SCHEMBL16448619 | 0.87 | SCN9A (0.64) | SCN9ASCN5A | |
| SCHEMBL15537287 | 0.87 | SCN9A (0.67) | SCN9ASCN5A | |
| SCHEMBL15535770 | 0.86 | SCN9A (0.56) | SCN9A | |
| SCHEMBL16448614 | 0.85 | SCN9A (0.69) | SCN9ASCN5A | |
| SCHEMBL15535926 | 0.85 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL15536309 | 0.84 | SCN9A (0.57) | SCN9ASCN5A | |
| SCHEMBL16448642 | 0.83 | SCN9A (0.71) | SCN9ASCN5A | |
| SCHEMBL16758808 | 0.83 | SCN9A (0.55) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166939-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016007534-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2016-01-14 | — | — | WO | disclosed |
| EP-2855428-A1 | N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN | Genentech, Inc. (US) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013177224-A1 | N-SUBSTITUTED BENZAMIDES AND THEIR USE IN THE TREATMENT OF PAIN | GENENTECH, INC. (US) | 2013-11-28 | — | — | WO | disclosed |