Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15537433 | 0.93 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15539375 | 0.92 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15548960 | 0.82 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15537753 | 0.81 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15607662 | 0.81 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15551163 | 0.81 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15560728 | 0.81 | PDE10A (1.00) | PDE10A | |
| SCHEMBL15538977 | 0.80 | PDE10A (1.00) | PDE10A | |
| SCHEMBL19561028 | 0.80 | PDE10A (0.78) | PDE10A | |
| SCHEMBL15537940 | 0.79 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855455-A1 | TRIAZOLO COMPOUNDS AS PDE10 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2015-04-08 | — | — | EP | disclosed |
| WO-2013178572-A1 | TRIAZOLO COMPOUNDS AS PDE10 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-12-05 | — | — | WO | disclosed |