Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 20/20 | 0.75 |
| ▸ | PDE4A | P27815 | 18/20 | 0.75 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.75 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.75 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957705 | 0.86 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL6954457 | 0.81 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL1553355 | 0.79 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL8269400 | 0.77 | PDE4D (0.64) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL5016433 | 0.74 | PDE4D (0.58) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL6958092 | 0.74 | PDE4D (0.78) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL6950213 | 0.73 | PDE4D (0.68) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL6963861 | 0.73 | PDE4D (0.75) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL8268013 | 0.73 | PDE4D (0.67) | PDE4DPDE4APDE4BPDE4CPDE11A | |
| SCHEMBL1553036 | 0.72 | PDE4D (0.69) | PDE4DPDE4APDE4BPDE4CPDE11A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934307-B1 | SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE | AVENTIS PHARMA LTD (GB) | 2011-04-27 | — | — | EP | disclosed |
| EP-2223920-A2 | Substituted azabicyclic compounds | Aventis Pharma Limited (GB) | 2010-09-01 | — | — | EP | disclosed |