Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22401637 | 1.00 | TSHR (0.65) | TSHREPHX1RAD52NPSR1NAAA | |
| SCHEMBL15537683 | 0.98 | TSHR (0.61) | TSHREPHX1RAD52NPSR1NAAA | |
| SCHEMBL6663600 | 0.92 | TSHR (0.53) | TSHREPHX1RAD52NPSR1NAAA | |
| SCHEMBL31622797 | 0.92 | TSHR (0.74) | TSHREPHX1RAD52NPSR1NAAA | |
| SCHEMBL5871868 | 0.92 | TSHR (0.74) | TSHREPHX1RAD52NPSR1NAAA | |
| SCHEMBL31622783 | 0.92 | TSHR (0.74) | TSHREPHX1RAD52NPSR1NAAA | |
| SCHEMBL6658710 | 0.92 | TSHR (0.74) | TSHREPHX1RAD52NPSR1NAAA | |
| SCHEMBL6656457 | 0.92 | TSHR (0.74) | TSHREPHX1RAD52NPSR1NAAA | |
| SCHEMBL31622788 | 0.92 | TSHR (0.74) | TSHREPHX1RAD52NPSR1NAAA | |
| SCHEMBL31622794 | 0.92 | TSHR (0.74) | TSHREPHX1RAD52NPSR1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021231288-A1 | IMPROVED DICARBONYL SUBSTITUTED-1-ALKENE COMPOSITIONS | NIPPON SHOKUBAI CO., LTD. (JP) | 2021-11-18 | — | — | WO | claimed |
| WO-2021162938-A1 | COPOLYMERS OF DICARBONYL SUBSTITUTED-1-ALKENE AND OLEFINS AND METHODS TO MAKE THEM | SIRRUS, INC. (US) | 2021-08-19 | — | — | WO | claimed |
| EP-3789408-A1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | Sirrus, Inc. (US) | 2021-03-10 | — | — | EP | claimed |
| EP-3786199-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | Sirrus, Inc. (US) | 2021-03-03 | — | — | EP | claimed |
| CN-107075037-B | Polymer comprising one or more 1, 1-disubstituted alkene compounds and polymer compositions thereof | 赛鲁斯股份有限公司 | 2021-02-09 | — | — | CN | claimed |
| EP-3191530-B1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | SIRRUS INC (US) | 2020-11-11 | — | — | EP | claimed |
| EP-3191533-B1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS INC (US) | 2020-11-04 | — | — | EP | claimed |
| CN-111825785-A | Emulsion polymers, emulsion processes and polymer compositions comprising one or more 1, 1-disubstituted alkene compounds | 赛鲁斯股份有限公司 | 2020-10-27 | — | — | CN | claimed |
| EP-3683267-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | Sirrus, Inc. (US) | 2020-07-22 | — | — | EP | claimed |
| EP-3191546-B1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS INC (US) | 2020-07-22 | — | — | EP | claimed |
| US-9617354-B2 | Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound | SIRRUS, INC. (US) | 2017-04-11 | — | — | US | claimed |
| WO-2016195818-A1 | ELECTROINITIATED POLYMERIZATION OF COMPOSITIONS HAVING A 1,1-DISUBSTITUTED ALKENE COMPOUND | SIRRUS, INC. (US) | 2016-12-08 | — | — | WO | claimed |
| US-20160347871-A1 | ELECTROINITIATED POLYMERIZATION OF COMPOSITIONS HAVING A 1,1-DISUBSTITUTED ALKENE COMPOUND | SIRRUS, INC. | 2016-12-01 | — | — | US | claimed |
| US-20160096906-A1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | NIPPON SHOKUBAI CO., LTD. (JP) | 2016-04-07 | — | — | US | claimed |
| US-20160096907-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS, INC. | 2016-04-07 | — | — | US | claimed |
| WO-2016040261-A1 | POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS AND POLYMER COMPOSITIONS THEREOF | SIRRUS, INC. (US) | 2016-03-17 | — | — | WO | claimed |
| WO-2016040012-A1 | EMULSION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, EMULSION METHODS, AND POLYMER COMPOSITIONS | SIRRUS, INC. (US) | 2016-03-17 | — | — | WO | claimed |
| US-20160068616-A1 | SOLUTION POLYMERS INCLUDING ONE OR MORE 1,1-DISUBSTITUTED ALKENE COMPOUNDS, SOLUTION POLYMERIZATION METHODS, AND POLYMER COMPOSITIONS | SIRRUS, INC. | 2016-03-10 | — | — | US | claimed |
| US-9279022-B1 | Solution polymers including one or more 1,1-disubstituted alkene compounds, solution polymerization methods, and polymer compositions | SIRRUS, INC. (US) | 2016-03-08 | — | — | US | claimed |
| US-9217098-B1 | Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound | SIRRUS, INC. (US) | 2015-12-22 | — | — | US | claimed |